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pharmacology

Analgesics and Pharmacological Pain Management

Analgesics range from non-opioids to opioids. Nurses apply the WHO analgesic ladder, monitor for side effects such as respiratory depression, and assess pain effectively.

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Key Points to Know

What you must know about Analgesics

1

Non-opioids include paracetamol and NSAIDs (e.g., ibuprofen, diclofenac).

2

Opioids include morphine, pethidine, codeine, and tramadol.

3

The WHO analgesic ladder: step 1 non-opioid, step 2 weak opioid, step 3 strong opioid — with adjuvants.

4

Morphine can cause respiratory depression, constipation, and sedation.

5

Naloxone is the antidote for opioid overdose/respiratory depression.

6

NSAIDs can cause gastric irritation and are given with or after food.

NMCN Exam Tips

How this topic appears in the NMCN exam

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Respiratory rate is the key parameter to monitor before/after opioids.

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Naloxone reverses opioid toxicity — a commonly tested antidote.

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Know the WHO analgesic ladder order (non-opioid → weak → strong opioid).

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Constipation is an expected opioid side effect requiring proactive management.

Practice Question

Test yourself

Before administering morphine to a post-operative patient, which assessment is MOST important for the nurse to perform?

A.Blood glucose level
B.Respiratory rate✓ Correct
C.Bowel sounds
D.Skin turgor

Explanation

Morphine can cause respiratory depression. Assessing the respiratory rate before administration (and withholding if the rate is low, e.g., below 12/min) is the priority safety action.

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