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pharmacology

Psychotropic (Mental Health) Medications

Psychotropic drugs include antipsychotics, antidepressants, mood stabilisers, and anxiolytics. Nurses monitor for specific serious effects such as EPS and lithium toxicity.

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Key Points to Know

What you must know about Mental Health Meds

1

Antipsychotics (e.g., haloperidol, chlorpromazine) can cause extrapyramidal side effects (EPS).

2

Neuroleptic malignant syndrome (high fever, rigidity, altered consciousness) is a medical emergency.

3

Lithium has a narrow therapeutic range; monitor levels and watch for toxicity.

4

Maintain adequate salt and fluid intake with lithium — dehydration raises lithium levels.

5

SSRIs (e.g., fluoxetine) are common antidepressants; watch for serotonin syndrome.

6

Antidepressants may take 2–4 weeks to reach full effect — important for patient teaching.

NMCN Exam Tips

How this topic appears in the NMCN exam

EPS (tremor, rigidity, dystonia) is the classic antipsychotic side effect.

Lithium toxicity signs: nausea, diarrhoea, tremor, confusion — hold and report.

Antidepressants take weeks to work; reassure and monitor suicide risk early.

Neuroleptic malignant syndrome = emergency (fever + rigidity).

Practice Question

Test yourself

A patient on lithium therapy presents with coarse tremors, vomiting, diarrhoea, and confusion. The nurse should suspect:

A.A normal therapeutic response
B.Lithium toxicity✓ Correct
C.An allergic reaction
D.Opioid withdrawal

Explanation

These are classic signs of lithium toxicity. Lithium has a narrow therapeutic range, and the nurse should withhold the drug, check the lithium level, and notify the physician. Dehydration and low sodium increase toxicity risk.

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